The chief executive of Cathay Pacific, Rupert Hogg, has resigned in the wake of the protests in Hong Kong.
Paul Loo is also leaving as chief customer and commercial officer.
Mr Hogg said: “These have been challenging weeks for the airline and it is right that Paul and I take responsibility as leaders of the company.”
Mr Hogg warned on Monday staff could be fired if they “support or participate in illegal protests” in Hong Kong.
But the previous week, Cathay Pacific had told its staff it would not stop them joining the pro-democracy demonstrations currently sweeping Hong Kong.
The airline’s chairman, John Slosar, said it was time to put “a new management team in place who can reset confidence and lead the airline to new heights”.
Cathay Pacific said in a statement that Mr Hogg had been replaced by Tang Kin Wing Augustus and Mr Loo by Ronald Lam.
Hong Kong International Airport has been closed this week in the wake of massive anti-government protests that have paralysed one of Asia’s key transport hubs.
Mr Slosar said that while Mr Hogg and his team had executed a three-year turnaround plan, “recent events have called into question Cathay Pacific’s commitment to flight safety and security and put our reputation and brand under pressure”.
“This is regrettable as we have always made safety and security our highest priority,” he said.
The new bosses “have the experience and depth of knowledge of aviation and our people to be strong and effective leaders of Cathay Pacific at this sensitive time”, he added.